Lipid Disorders
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Novel PCSK9 Inhibitor Reduced LDL by 50%
Study finds new PCSK9 inhibitor cut LDL in half after a year, with monthly small-volume injection.
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Early Olezarsen Results Show 50% Reduction in Triglycerides
Antisense treatment that inhibits ApoC-III expression can significantly reduce triglyceride, trial finds.
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Magnesium and Metabolic Syndrome: Any Connection?
Chronic hypomagnesemia may play a role in the pathogenesis of metabolic disorders.
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Statins Tied to Lower Mortality, Even With Comorbid Dementia
“It may be time to reconsider the broad recommendations to avoid or deprescribe statins in nursing home residents.”
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Phase 2 Results: Zerlasiran siRNA Drug Lowers Lp(a) by 90%
At 36 weeks, siRNA reduced Lp(a) from baseline when compared to placebo, says company.
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Nurse-Led Strategy Reduces Cholesterol, BP in HIV
The strategy involved home blood pressure monitoring and electronic health record tools.
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Higher Dietary Niacin Tied to Lower Mortality Risk in MASLD
Data suggested a significant interaction between niacin and diabetes with the risk of all-cause mortality.
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Does worsening metabolic syndrome increase the risk of developing cancer?
Elevated trajectories of metabolic syndrome were associated with an elevated overall cancer risk.
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Sex Matters in Postprandial Response to Hypoxemia
Men had higher plasma triglyceride levels after hypoxemia, study finds, highlighting potential impact of OSA.
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Hypertriglyceridemia in Young Adults Raises Red Flag
High triglycerides are linked to risk for type 2 diabetes.
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Higher HDL Tied to Prediabetes Reversion — Up to a Point
After a median follow-up of nearly 3 years, 43% of patients with prediabetes had a reversion to normoglycemia; those with higher HDL-C levels had...